SleepSupport - 4 Bottles 120 Day Supply (Save 30%)
by calmsupport4 Bottles of SleepSupport (240 capsules, 4 month supply)
SleepSupport is an all natural and organic sleep aid designed to help relieve stress and support relaxation. SleepSupport was formulated to help with difficulty falling or staying asleep, as well as support feelings of relaxation and calm.*
• Fully Organic Herbal Powder (Not Extracts)
• We Only Use Active Vitamins In Our Products
• All Natural - No Dyes, No Artificial Coloring, and No Magnesium Stearate
• Vegetarian Formula
Recommended Dosage: Take 1 to 2 capsules 30 minutes before bed to help improve sleep.
Each bottle contains 60 capsules.
Ingredients:
Organic Ashwaganda (Withania somnifera): Ashwaganda has been used historically for thousands of years for a great many beneficial actions. Modern research has confirmed that Ashwaganda has relaxing properties and can help people physically and psychologically deal with stress [1]. Ashwaganda seems to work by modulating GABA, the main inhibitory neurotransmitter in the body [2]. Research has shown supplementation with Ashwganda improves sleep [3]. Withania has also been shown to have potent anti-inflammatory properties with inhibition against NF-kB[4] and TNF-a [5] [6] [7].
Organic Hops (Humulus lupulus): Hops are a common flavoring agent used to impart the bitter flavor of modern beers. It is also an incredibly useful medicinal plant which helps reduce stress and anxiety and can help promote more restful sleep [8] [9].
Magnesium Citrate: a critically important mineral, which supports the brain, energy, helps decrease stress, and can help relax tight muscles. This form is more absorbable than other commonly available forms [10] [11]. http://www.drweil.com/drw/u/ART02805/magnesium.html
Melatonin: a hormone produced in the pineal gland of the brain that signals the body when its time to go to sleep. Can be used safely to help with restlessness and insomnia. Melatonin supplementation has been shown to be useful for sleep disturbances and insomnia [12] [13]. Melatonin has been shown in studies to decrease delirium in older adults. Melatonin is safe for short term and long-term use [14] [15].
Organic Wild Lettuce (leaf) (Lactuca virosa): Wild lettuce has been used historically to treat nervousness, anxiety, and insomnia. Modern research has validated these uses and has found both sedative and pain-relieving molecules in this herb [16].
Organic Valerian (Valeriana officinalis): Valerian has been used for thousands of years around the world to treat several disorders including restlessness, nervousness and insomnia [17] [18] [19]. For many people it helps fight anxiety, nervousness, lowers heart rate, which relieves hypertension. In WWII Valerian root was used in England to reduce the stress of air raids [20].
Organic Passion Flower (Passiflora incarnata): Many people find Passionflower a soothing sleep-aid and in supporting relaxation in times of stress. Scientists believe that passionflower works by increasing levels of a chemical called gamma-aminobutyric acid (GABA) in the brain [21]. GABA reduces the activity of some brain cells, inducing a greater state of relaxation [22] [23].
L-Theanine: L-Theanine as L-TeaActive(TM) is an amino acid found in green tea and has been shown to have a direct influence on brain activity, such as reducing stress [25]. It has also been shown to have positive effects on anxiety in patients with schizophrenia [26].
Glycine: Glycine is a sweet-tasting, non-essential amino acid that has been shown to have a multitude of benefits in the body. Glycine interacts with the NMDA and Glycine receptors in the brain [30] and supplementation has been shown to benefit insomnia, improved sleep quality and decreased daytime sleepiness [32] [33]. Glycine has broad spectrum of anti-inflammatory, cytoprotective and immunomodulatory properties [34].
L-Tryptophan: Tryptophan is an important amino acid that is converted to 5-HTP (5-hyrdoxytryptophan) and then to Serotonin in the body. Serotonin transmits signals between nerve cells and improves mood. Low serotonin levels are implicated in depression [27]. Tryptophan levels have been shown to be lower in those suffering from insomnia [28]. Tryptophan intake has been associated with lower levels of depression and improved sleep [29].
Sources:
[1] Cell Mol Life Sci. 2015 Dec;72(23):4445-60. doi: 10.1007/s00018-015-2012-1.
[2] J Ethnopharmacol. 2015 Aug 2;171:264-72. doi: 10.1016/j.jep.2015.05.058.
[3] Mol Cell Biochem. 2017 Mar;427(1-2):91-101. doi: 10.1007/s11010-016-2900-1.
[4] Phytother Res. 2007 Oct;21(10):905-13.
[5] Mol Cell Biochem. 2017 Mar;427(1-2):91-101. doi: 10.1007/s11010-016-2900-1
[6] J Ethnopharmacol. 2011 Sep 1;137(1):231-5. doi: 10.1016/j.jep.2011.05.017.
[7] Afr J Tradit Complement Altern Med. 2017 Jan 13;14(2):319-324
[8] Acta Physiol Hung. 2012 Jun;99(2):133-9. doi: 10.1556/APhysiol.99.2012.2.6.
[9] Holist Nurs Pract. 2009 Jul-Aug;23(4):253-6. doi: 10.1097/HNP.0b013e3181aed09d.
[10] (J Am Coll Nutr. 1990 Feb;9(1):48-55)(Clin Biochem Rev. 2003 May; 24(2): 47–66)
[11] Acta Anaesthesiol Taiwan. 2016 Jul 16. pii: S1875-4597(15)30016-3
[12] Ferguson SA, Rajaratnam SM, Dawson D. Melatonin agonists and insomnia. Expert Review of Neurotherapeutics. 2010;10(2):305–318.
[13] Herxheimer A, Petrie KJ. Melatonin for the prevention and treatment of jet lag. Cochrane Database of Systematic Reviews. 2002;(2):CD001520 [edited 2009]. Accessed at www.thecochranelibrary.com on April 10, 2014.
[14] Gooneratne NS. Complementary and alternative medicine for sleep disturbances in older adults. Clinics in Geriatric Medicine. 2008;24(1):121–138.
[15] van Geijlswijk IM, Korzilius HP, Smits MG. The use of exogenous melatonin in delayed sleep phase disorder: a meta-analysis. Sleep. 2010;33(12):1605–1614.
[16] Iran J Pharm Res. 2013 Spring;12(2):401-6.
[17] Blumenthal M, Goldberg A, Brinckmann J. Herbal Medicine: Expanded Commission E Monographs. Newton, MA: Integrative Medicine Communications; 2000:394-400.
[18] Balderer G, Borbely AA. Effect of valerian on human sleep. Psychopharmacology (Berl). 1985;87(4):406-409.
[19] Vorbach EU, Gortelmeyer R, Bruning J: Treatment of insomnia: effectiveness and tolerance of a valerian extract [in German]. Psychopharmakotherapie 3: 109-115, 1996.
[20] Turner W: Of Valerianae. In: Chapman GTL, McCombie F, Wesencraft A, eds. A New Herbal, Parts II and III. Cambridge: Cambridge University Press, 1995: 464-466, 499-500, 764-765.
[21] J. Ethnopharmacol., 8(1-2): 239-244
[22] Fitoterapia. 2001 Dec;72(8):922-6.
[23] J Ethnopharmacol. 2013 Dec 12;150(3):791-804. doi: 10.1016/j.jep.2013.09.047.
[25] Trends in Food Science & Tech . 1999;10;199-204.* Nobre AC, Rao A, Owen GN.
[26] J Clin Psychiatry . 2011;72(1):34-42.
[27] Pharmacol Biochem Behav. 2002 Apr;71(4):857-65.
[28] Pak J Pharm Sci. 2017 Jul;30(4(Suppl.)):1431-1438.
[29] J Nutr. 2016 Dec;146(12):2609S-2615S.
[30] Oxid Med Cell Longev. 2017; 2017: 1716701
[32] Front Neurol. 2012 Apr 18;3:61.
[33] J Pharmacol Sci. 2012;118(2):145-8. Epub 2012 Jan 27
[34] Mini Rev Med Chem. 2017;17(1):15-32
Warnings: As with any supplement, if you are taking medication or have a medical condition, consult your doctor before use. Not formulated for use by children or those pregnant or lactating. Do not exceed recommended use. May cause drowsiness, do not operate machinery. Keep out of reach of children.
